- Born in Illinois.
- A.B., Webster College; M.A., Notre Dame University
- Was a member of President Kennedy's Advisory Panel on Research and Development in Education and the steering committee for Project Head Start.
- Helped secure numerous grants from major foundations, including the National Science Foundation and the Ford Foundation, which helped fund innovations in the teacher education curriculum.
- Was instrumental in the transfer of ownership of the college to a lay board in 1967.
Jacqueline Grennan Wexler resigned her position at Webster College in 1969 and later became president of Hunter College in 1970. A finding aid containing a detailed biographical sketch and information about her years at Hunter College is available.